基本情况
姓名：李苏华
性别：男
出生年月：1983-05
籍贯：江苏姜堰 （江西德安人）
职位：教授，博士生导师
联系方式
电话：暂未填写
传真：暂未填写
通讯地址：广州市番禺区大学城外环东路132号中大东校区化学材料大楼A1006
邮编：510006
个人网站：暂未填写
教育经历
2007.09–2012.07 中国科学院上海有机化学研究所，有机化学博士 导师：麻生明 院士
2002.09–2006.06 南京大学 化学学士学位
工作经历
2017.07–至今 线上赌博app-赌博软件下载
，教授，博士生导师
2014.07–2017.06 The Scripps Research Institute 博士后 合作导师：K. Barry Sharpless教授
2012.08–2014.07 The Scripps Research Institute 博士后 合作导师：Jin-Quan Yu教授
2006.08–2007.09 康化（上海）新药研发有限公司
讲授课程
《有机合成化学》（课程负责人）
《金属有机化学》
《现代化学研究方法与技术》
科研方向
通过发展新试剂和新方法来探索经济、高效的有机合成反应，发展基础化学品的绿色合成新路线，实现资源化合物的高效转化，寻求在能源、环境、材料以及生物中的应用。
课题组长期招聘博士后。我们热诚欢迎硕士和博士研究生加入本课题组，同时欢迎本科生利用课余时间来本组短期或长期交流学习
科研项目
中山大学“百人计划”启动经费
获奖情况
. 黄文洪有机化学奖教金，2021
. 2021 Horizon Prize: Robert Robinson Award in Synthetic Chemistry (Team awards for the development of multidimensional click chemistry), RSC, 2021
. 2011年度麻生明小组“研究贡献奖”, 2012
. 布劳恩奖学金, 布劳恩惰性气体系统有限公司, 2011
. 中国科学院院长优秀奖, 2011
论著一览
47. Shun Liu, Qidong Zhang, Ji Ma, Xiankuan Huo, Lingbo Ji, Baojiang He, Guobi Chai, Qingzhao Shi, Jian Mao, Hui Xi, Wu Fan,* and Suhua Li*
Highly Regio- and Stereoselective Dehydration of Allylic Alcohols to Conjugated Dienes via 1,4-syn-Elimination with H2 Evolution
46. Zhiyuan Peng, Shoujun Sun, Meng-Meng Zheng, Yangyang Li, Xixi Li, Suhua Li, Xiao-Song Xue,* Jiajia Dong,* Bing Gao*
Enantioselective sulfur(VI) fluoride exchange reaction of iminosulfur oxydifluorides
45. Shouzhi Zhang, Wu Fan,* Suhua Li*
Synthesis and Applications of Trifluoromethylphosphines
Eur. J. Org. Chem. 2024, 27, e202301169.
44. Bingyin Meng,# Luyao Liu,# Xiaotong Shen, Wu Fan,*, and Suhua Li*
Pyridine N-Oxide-Promoted Cobalt-Catalyzed Dioxygen-Mediated Methane Oxidation
43. Deqian Peng,# Shouzhi Zhang,# Wu Fan, Yuan Wen, Suhua Li*
Zn-Mediated Scalable Synthesis of Trifluoromethylphosphines from Phosphine Chlorides and CF3Br
Org. Lett. 2023, 25, 3892−3897. (Highlighted in Organic Chemistry Portal)
42. Yuan Wen, Ruifang Nie, Bo Li, Suhua Li*
Ligand-Promoted Bifunctional Cobalt-Catalyzed Carbonylation-Polymerization of Epoxides: One Step to Polyhydroxyalkanoates
41. Luyao Liu, Wu Fan, Suhua Li*
NaCl-Promoted Cobalt-Catalyzed Dioxygen-Mediated Methane Oxidation to Methylene Bis(trifluoroacetate) with a Dramatic Salt Effect
40. Bo Li, Shihao Liu, Wu Fan, Xiaotong Shen, Jing Xu, Suhua Li*
Ligand enabled none-oxidative decarbonylation of aliphatic aldehydes
Chin. Chem. Lett. 2023, 34, 108027.
39. Licheng Sang, Weiyi Yang, Shuang Gao, Suhua Li, Jian Ku Shang, Qi Li,*
Photocatalytic activity of polyacrylonitrile under simulated solar illumination
Chem. Eng. J., 2022, 434, 134697.
38. Liangzhi Pang, Qilin Sun, Zhan Huang, Suhua Li,* Qiankun Li*
Cobalt–Tertiary Amine Mediated Peroxy-trifluoromethylation and -halodifluoromethylation of Alkenes with CF2XBr (X = F, Cl, Br) and tert-Butyl Hydroperoxide
37. Qilin Sun, Liangzhi Pang, Shuxian Mao, Wu Fan, Yuyi Zhou, Jing Xu, Suhua Li* Qiankun Li*
Cobalt-Catalyzed Hydroxyperfluoroalkylation of Alkenes with Perfluoroalkyl Bromides and Atmospheric Oxygen
36. Deqian Peng, Wu Fan, Xueqi Zhao, Wei Chen, Yuan Wen, Li Zhang, Suhua Li*
Zinc-Brønsted Acid Mediated Practical Hydrotrifluoromethylation of Alkenes with CF3Br
Org. Chem. Front., 2021, 8, 6356.
35. Suhua Li,* Gencheng Li, Bing Gao, Sidharam P. Pujari,Xiaoyan Chen, Hyunseok Kim, Feng Zhou, Liana M. Klivansky, Yi Liu, Hafedh Driss, Dong-Dong Liang, Jianmei Lu, Peng Wu,* Han Zuilhof,* John Moses,* K. Barry Sharpless,*
SuFExable polymers with helical structures derived from thionyl tetrafluoride
34. Luyao Liu, Wu Fan, Wei Chen, Xiaoyan Chen, Suhua Li*
KF-Promoted Copper-Catalyzed Highly Efficient and Selective Oxidation of Methane and other Alkanes with Dramatic Additive Effect
Catal. Sci. Technol., 2021, 11, 4962.
33. Qiankun Li, Wu Fan, Deqian Peng, Bingyin Meng, Shaohan Wang, Rui Huang, Shihao Liu, and Suhua Li*
Cobalt−Tertiary-Amine-Mediated Hydroxytrifluoromethylation of Alkenes with CF3Br and Atmospheric Oxygen
32. Gabriel J. Brighty#, Rachel C. Botham#, Suhua Li#, Luke Nelson, David E. Mortenson, Gencheng Li, Christophe Morisseau, Hua Wang, Bruce D. Hammock, K. Barry Sharpless, Jeffery W. Kelly
Using sulfuramidimidoyl fluorides that undergo sulfur(VI) fluoride exchange for inverse drug discovery
31. A. S. Barrow, C. J. Smedley, Q. Zheng, S. Li, J. Dong, J. E. Moses*
The growing applications of SuFEx click chemistry
Chem. Soc. Rev. 2019, 48, 4731.
30. Feng Liu#, Hua Wang#, Suhua Li, Grant A. L. Bare, Xuemin Chen, Chu Wang, John E. Moses, Peng Wu, K. Barry Sharpless*
Biocompatible SuFEx Click Chemistry: Thionyl Tetrafluoride (SOF4)-Derived Connective Hubs for Bioconjugation to DNA and Proteins
Angew. Chem. Int. Ed. 2019, 58, 8029.
29. Digvijay Gahtory, Rickdeb Sen, Sidharam Pujari, Suhua Li, Qinheng Zheng, John E. Moses,* K. Barry Sharpless,* Han Zuilhof*
Quantitative and Orthogonal Formation and Reactivity of SuFEx Platforms
Chem. Eur. J. 2018, 24, 10550.
28. Zilei Liu#, Jie Li#, Suhua Li#, Gencheng Li, K. Barry Sharpless, Peng Wu*,
SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization
J. Am. Chem. Soc., 2018, 140, 2919.
27. Bing Gao, Suhua Li, Peng Wu, John E. Moses, K. Barry Sharpless*
SuFEx Chemistry of Thionyl Tetrafluoride (SOF4) with Organolithium Nucleophiles: Synthesis of Sulfonimidoyl Fluorides, Sulfoximines, Sulfonimidamides, and Sulfonimidates
Angew. Chem. Int. Ed. 2018, 57, 1939.
26. David E. Mortenson, Gabriel J. Brighty, Lars Plate, Grant Bare, Wentao Chen, Suhua Li, Hua Wang, Benjamin F. Cravatt, Stefano Forli, Evan T. Powers, K. Barry Sharpless*Ian A. Wilson*, Jeffery W. Kelly*
“Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates
J. Am. Chem. Soc. 2018, 140, 200.
25. Wan Jung Kim, Keith Korthals, Suhua Li, Christine Le, Jaroslaw Kalisiak, K. Barry Sharpless, Valery V. Fokin, Yukiko Miyamoto, Lars Eckmann*
Click chemistry-facilitated structural diversification of nitrothiazoles, nitrofurans and nitropyrroles enhances antimicrobial activity against Giardia lamblia
Antimicrob. Agents Chemother. 2017, 61, e02397-16.
24. Bukeyan Miao, Yangguangyan Zheng, Penglin Wu, Suhua Li, Shengming Ma*
Bis(cycloocta-1,5-diene)nickel-Catalyzed Carbon Dioxide Fixation for Stereoselective Synthesis of 3-Alkylidene-2-indolinones
Adv. Synth. Catal. 2017, 359, 1691.
23. Suhua Li, Peng Wu, John E. Moses, K. Barry Sharpless*
Multidimensional SuFEx Click Chemistry: Sequential Sulfur(VI) Fluoride Exchange Connections of Diverse Modules Launched From An SOF4 Hub
Angew. Chem. Int. Ed. 2017, 56, 2903. (VIP paper, highlighted in C&E News, 2017, 95, 10; Chemistry World)
22. Haiyan Fu, Peng-Xiang Shen, Jian He, Fanglin Zhang, Suhua Li, Peng Wang, Tao Liu, Jin-Quan Yu*
Ligand-Enabled Alkynylation of C(sp3)-H Bonds with Pd(II) Catalysts
Angew. Chem. Int. Ed. 2017, 56, 1873.
21. Wentao Chen#, Jiajia Dong#, Lars Plate#, David E. Mortenson, Gabriel J. Brighty, Suhua Li, Yu Liu, Andrea Galmozzi, Peter S. Lee, Jonathan J. Hulce, Benjamin F. Cravatt, Enrique Saez, Evan T. Powers, Ian A. Wilson, K. Barry Sharpless*, Jeffery W. Kelly*
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
J. Am. Chem. Soc. 2016, 138, 7353.
20. Bukeyan Miao, Suhua Li, Gen Li and Shengming Ma*
Cyclic Anti-Azacarboxylation of 2‑Alkynylanilines with Carbon Dioxide
Org. Lett. 2016, 18, 2556. (Highlighted in Synfacts, 2016, 12, 890.)
19. Suhua Li, Ru-Yi Zhu, Kai-Jiong Xiao and Jin-Quan Yu*
Ligand-Enabled Arylation of γ-C-H Bonds
Angew. Chem. Int. Ed. 2016, 55, 4317.
18. Enxuan Zhang*, Jiaze Tang, Suhua Li, Peng Wu, John E. Moses and K. Barry Sharpless*
Chemoselective Synthesis of Polysubstituted Pyridines From Heteroaryl Fluorosulfates
Chem. Eur. J. 2016, 22, 5692-5697. (Highlighted in Synfacts, 2016, 12, 617.)
17. Wentao Chen#, Jiajia Dong#, Suhua Li, Yu Liu, Yujia Wang, Leonard Yoon, Peng Wu, K. Barry Sharpless*, Jeffery W. Kelly*
Synthesis of Sulfotyrosine-Containing Peptides by Incorporating Fluorosulfated Tyrosine Using an Fmoc-Based Solid-Phase Strategy
Angew. Chem. Int. Ed. 2016, 55, 1835.
16. Ru-Yi Zhu, Keita Tanaka, Gen-Cheng Li, Jian He, Hai-Yan Fu, Suhua Li and Jin-Quan Yu*
Ligand-Enabled Stereoselective β-C(sp3)–H Fluorination: Synthesis of Unnatural Enantiopure anti-β-Fluoro-α-amino Acids
J. Am. Chem. Soc. 2015, 137, 7067.
15. Xiao-Chen Wang, Wei Gong, Li-Zhen Fang, Ru-Yi Zhu, Suhua Li, Keary M. Engle and Jin-Quan Yu*
Ligand-enabled meta-C–H activation using a transient mediator
14. Gang Chen, Toshihiko Shigenari, Pankaj Jain, Zhipeng Zhang, Zhong Jin, Jian He, Suhua Li, Claudio Mapelli, Michael M. Miller, Michael A. Poss, Paul M. Scola, Kap-Sun Yeung and Jin-Quan Yu*
Ligand-Enabled beta-C–H Arylation of alpha-Amino Acids Using a Simple and Practical Auxiliary
J. Am. Chem. Soc. 2015, 137, 3338.
13. Suhua Li, Gang Chen, Chen-Guo Feng, Wei Gong and Jin-Quan Yu*
Ligand-Enabled γ-C–H Olefination and Carbonylation: Construction of β-Quaternary Carbon Centers
J. Am. Chem. Soc. 2014, 136, 5267. (Highlighted in Organic Chemistry Portal, 2015, Jan 26th)
12. Jian He#, Suhua Li#, Youqian Deng, Haiyan Fu, Brian N. Laforteza, Jillian E. Spangler, Anna Homs and Jin-Quan Yu*
Ligand-Controlled C(sp3)–H Arylation and Olefination in Synthesis of Unnatural Chiral α–Amino Acids,
Science, 2014, 343, 1216. (Highlighted in C&EN News, 2014, 92, 5.)
11. Chen-Guo Feng, Mengchun Ye, Kai-Jiong Xiao, Suhua Li and Jin-Quan Yu*
Pd(II)-Catalyzed Phosphorylation of Aryl C–H Bonds
J. Am. Chem. Soc. 2013, 135, 9322.
10. Suhua Li, Juntao Ye, Weiming Yuan and Shengming Ma*
Highly Regioselective Three-component Palladium-Catalyzed Synthesis of 5-Vinyloxazolidin-2-one from 2,3-Allenyl Amines, Organic Iodides and Carbon Dioxide
9. Juntao Ye, Suhua Li and Shengming Ma*
Gorlos-phos: Addressing the Stereoselectivity in Palladium-catalyzed Exo-mode Cyclization of Allenes with a Nucleophilic Functionality
Org. Biomol. Chem. 2013, 11, 5370.
8. Suhua Li, Bukeyan, Miao, Weiming Yuan and Shengming Ma*
Carbometalation–Carboxylation of 2,3-Allenols with Carbon Dioxide: A Dramatic Effect of Halide Anion
Org. Lett., 2013, 15, 977. (Highlighted in Organic Chemistry Portal, Abstracts: //www.organic-chemistry.org/abstracts/lit3/945.shtm)
7. Juntao Ye, Suhua Li and Shengming Ma*
Palladium-Catalyzed Cyclization Reactions of 2,3-Allenyl Amines with Propargylic Carbonates
6. Suhua Li and Shengming Ma*
Quadri-Synergetic Effect for Highly Effective Carbon Dioxide Fixation and Its Application to Indoloquinolinone
Adv. Synth. Catal. 2012, 354, 2387.
5. Juntao Ye, Suhua Li, Bo Chen, Wu Fan, Jingqiang Kuang, Jinxian Liu, Yu Liu, Bukeyan Miao, Bao Wan, Yuli Wang, Xi Xie, Qiong Yu, Weiming Yuan and Shengming, Ma*
Catalytic Asymmetric Synthesis of Optically Active Allenes from Terminal Alkynes
4. Suhua Li and Shengming Ma*
CO2-Activation for γ-Butyrolactones and its Application in the Total Synthesis of (±)-Heteroplexisolide E
3. Suhua Li and Shengming Ma*
Highly Selective Nickel-Catalyzed Methyl-Carboxylation of Homopropargylic Alcohols for α-Alkylidene-γ-butyrolactones
Org. Lett. 2011, 13, 6046. (Highlighted in Synfacts, 2012, 8, 196.)
2. Suhua Li, Weiming Yuan and Shengming Ma*
Highly Regio- and Stereoselective Three-Component Nickel-Catalyzed syn-Hydrocarboxylation of Alkynes with Diethyl Zinc and Carbon Dioxide
Angew. Chem. Int. Ed. 2011, 50, 2578. (Highlighted in Nature China doi: 10.1038/nchina.2011.13; Angew. Chem. Int. Ed. 2011, 50, 6210.)
1. Shengming Ma*, Jinxian Liu, Suhua Li, Bo Chen, Jiajia Cheng, Jinqiang Kuan, Yu Liu, Baoqiang Wan, Yuli Wang, Juntao Ye, Qiong Yu, Weiming Yuan and Shichao Yu
Development of a General and Practical Iron Nitrate/TEMPO Catalyzed Aerobic Oxidation of Alcohols to Aldehydes/Ketones: Catalysis with Table Salt
Adv. Synth. Catal. 2011, 353, 1005.
